Efficacy data represents percent change from baseline and was collected from peer-reviewed published studies and / or FDA approved package inserts. Ranges reflect both inter-individual variability reported in the studies and dose ranging effects.

Lifestyle	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
smoking cessation	none	none	10-20	good	none	none
exercise	none	good	7-30	good	13-42	none
diet (TLC)	5-35	good	none	good	10-50	none

Statins	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
lovastatin (Mevacor)	20-32	minimal	5-8	good	6-10	bad
pravastatin (Pravachol)	22-34	minimal	2-12	good	11-24	none
simvastatin (Zocor)	26-47	minimal	8-16	good	12-33	none
fluvastatin (Lescol)	22-36	minimal	3-7	good	12-19	none
atorvastatin (Lipitor)	39-60	minimal	5-9	bad	19-37	bad
rosuvastatin (Crestor)	45-63	good	8-14	very good	10-35	none

Fibrates	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
gemfibrozil (Lopid)	4-23	good	12-25	none	35-60	none
fenofibrate (Tricor, Antara, Lofibra)	20-30	good	9-10	none	30-71	good

Omega-3-fatty acids (Lovasa)	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
Omega-3-fatty acids (Lovasa)	0-49	good	9-10	none	45-52	good

Resins	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
colestipol (Colestid)	20-25	minimal	0-4	none	5-15	none
cholestyramine (Questran)	20-25	minimal	0-4	none	5-15	none
colesevelam (WelChol)	15-18	minimal	3-11	none	9-10	none

Niacin (Niaspan...)	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
Niacin (Niaspan...)	5-14	very good	18-22	very good	21-28	good

Ezetimibe	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
Ezetimibe (Zetia)	18	good	1	none	7-9	none

Fixed Dose Combinations	LDL	LDL Size	HDL	HDL subtype	Triglycerides	Lp(a)
simvastatin/ezetimibe (Vytorin)	45-60	good	6-10	good	23-31	none
niacin/lovastatin (Advicor)	30-42	very good	20-30	very good	32-44	good
niacin/simvastatin (Simcor)	40-59	very good	25-33	very good	30-50	good